Publications
1. Brown, D.T., and T.F. Anderson (1969). Effect of host cell wall material on the adsorbability of cofactor-requiring T4. J. Virol. 4:94-108.
2. Brown, D.T., J.M. MacKenzie, and M.E. Bayer (1971). Mode of host cell penetration by bacteriophage oX174. J. Virol. 7:836- 846.
3. Brown, D.T., N.C. Brown, and B.T. Burlingham (1972). Morphology and physical properties of Staphylococcus Bacteriophage P11-M15. J. Virol. 9:664-671.
4. Waite, M.R.F., D.T. Brown, and E.R. Pfefferkorn (1972). Inhibition of Sindbis virus release by media of low ionic strength: an electron microscope study. J. Virol. 10:537-544.
5. Brown, D.T., M.R.F. Waite, and E.R. Pfefferkorn (1972). Morphology and morphogenesis of Sindbis virus as seen with freeze- etching techniques. J. Virol. 10:534-536.
6. Korenbrot, J.I., D.T. Brown, and R.A. Cone (1973). Membrane characteristics and osmotic behavior of isolated rod outer segments. J. Cell Biol. 56:389-398.
7. Brown, D.T., and B.T. Burlingham (1973). Penetration of host cell membranes by adenovirus 2. J. Virol. 12:386-396.
8. Burchard, R.P., and D.T. Brown (1973). Surface structure of gliding bacteria after freeze-etching. J. Bacteriology 114:1341- 1355.
9. Harrison, D.P., D.T. Brown, and V.C. Bode (1973). The lambda head tail joining reaction: purification, properties and structure of biologically active heads and tails. J. Mol. Biol. 70:437-449.
10. Brown, D.T., and J.B. Gliedman (1973). Morphological variants of Sindbis virus obtained from infected mosquito tissue culture cells. J. Virol. 12:1535-1539.
11. Doerfler, W., H. Burger, J. Ortin, E. Fanning, D.T. Brown, M. Wesphal, U. Winterhoff, B. Weiser, and J. Schick (1974). Integration of adenovirus DNA into the host cell genome. Cold Spring Harbor Symp. 1974, Vol. 34:505.
12. Burlingham, B.T., D.T. Brown, and W. Doerfler (1974). Incomplete particles of adenovirus types 2 and 12. I. Characteristics of the DNA associated with the incomplete adenovirions. Virol. 60:419-430.
13. Groneberg, J., D.T. Brown, and W. Doerfler (1975). Uptake and fate of the DNA of adenovirus type 2 in KB cells. Virol. 64:115.
14. Brown, D.T., and J.F. Smith (1975). Morphology of BHK-21 cells infected with Sindbis virus temperature-sensitive mutants in complementation groups D and E. J. Virol. 15:1262-1266.
15. Gliedman, J.B., J.F. Smith, and D.T. Brown (1975). Morphogenesis of Sindbis virus in cultured Aedes albopictus cells. J. Virol. 16:913-926.
16. Brown, D.T., J.F. Smith, J.B. Gliedman, B. Riedel, D. Filtzer, and D. Renz (1975). Morphogenesis of Sindbis virus in cultured mosquito cells. In E. Kurstak, and K, Maramorosch (eds.) “Invertebrate tissue culture.” Academic Press, p. 35-48.
17. Johnston, R.E., D.R. Tovell, D.T. Brown, and P. Faulkner (1975). Interfering passages of Sindbis virus: concomitant appearances of interference, morphological variants and truncated viral RNA. J. Virol. 16:951-958.
18. Brown, D.T., M. Westphal, B.T. Burlingham, U. Winterhoff, and W. Doerfler (1975). The structure and composition of the adenovirus type 2 core. J. Virol. 16:366-387.
19. Black, L.W., and D.T. Brown (1976). Morphological observations of E. coli cells infected with T4 phage head and internal protein defective mutants. J. Virol. 17:894-905.
20. Kemper, B., and D.T. Brown (1976). The function of gene 49 of bacteriophage T4. II. Intracellular development and structural analysis of very fast sedimenting DNA. J. Virol. 18:1000-1015.
21. Renz, D. and D.T. Brown (1976). Characteristics of Sindbis virus temperature-sensitive mutants in cultured BHK-21 and Aedes albopictus (mosquito) cells. J. Virol. 19:775-781.
22.Kania, J., and D.T. Brown (1976). The functional repressor parts of a tetrameric Lac repressor-B-galactosidase chimaera are organized as dimers. Proc. Nat. Acad. Sci. USA. 73 #10, pp, 3529-3533.
23. Brown, D.T., and B. Riedel (1977). Morphogenesis of vesicular stomatitis virus: electron microscope observations with freeze-fracture techniques. J. Virol. 21:601.
24. Smith, J.F., and D.T. Brown (1977). Envelopment of Sindbis virus: synthesis and organization of proteins in cells infected with wild-type and maturation defective mutants. J. Virol. 22:662.
25. Riedel, B., and D.T. Brown (1977). Role of extracellular virus in the maintenance of the persistent infection induced in Aedes albopictus (mosquito) cells by Sindbis virus. J. Virol. 23:554-561.
26. Riedel, B., and D.T. Brown (1979). Novel antiviral activity found in the media of Sindbis virus persistently infected mosquito (Aedes albopictus) cell cultures. J. Virol. 29:51-60.
27. Dunker, R., and D.T. Brown (1979). A tubular subviral structure produced in adenovirus infected KB cells. J. Virol. 31:568-574.
28. Eggers, H.J., B. Bode, and D.T. Brown (1979). Cytoplasmic localization of the uncoating of picornaviruses. Virol. 92:211- 218.
29. Scheefers, H., U. Scheefers-Borchel, J. Edwards and D.T. Brown (1980). Distribution of virus structural proteins and protein-protein interactions in plasma membrane of BHK cells infected with Sindbis or vesicular stomatitis virus. PNAS, 77:7277-7281.
30. Brown, D.T. (1980). “The Assembly of Alphaviruses.” In R.W. Schlesinger’s (ed,.) The Togaviruses, pp. 473-501. Academic Press, N.Y.
31. Erwin, C., and D.T. Brown (1980). Intracellular distribution of Sindbis virus membrane proteins in BHK-21 cells infected with wild-type virus and maturation defective mutants. J. Virol. 36:775-786.
32. Coombs, K., E. Mann, J. Edwards, and D.T. Brown (1981). Effects of chloroquine and cytochalasin B on the infection of cells by Sindbis virus and vesicular stomatitis virus. J. Virol. 37:1060-1065.
33. Scheefers-Borchel, U., H. Scheefers, J. Edwards, and D.T. Brown (1981). Sindbis virus maturation in cultured mosquito cells is sensitive to actinomycin D. Virol. 110:292-301.
34. Adams, R.H., and D.T. Brown (1982). Inhibition of Sindbis virus maturation after treatment of infected cells with trypsin. J. Virol. 41:692-702.
35. Wisseman, Jr., C.L., D.J. Silverman, A. Waddell, and D.T. Brown (1982). Penicillin-induced unstable intracellular formation of spheroplasts by Rickettsiae. J. of Infect. Diseases 146:147-158.
36. Erwin, C., and D.T. Brown (1983). Requirement of cell nucleus for Sindbis virus replication in cultured Aedes albopictus (mosquito) cells. J. Virol. 45:792-799.
37. Edwards, J., E. Mann, And D.T. Brown (1983). Conformational changes in Sindbis virus envelope proteins accompanying exposure to low pH. J. Virol. 45:1090-1097.
38. Mann, E., J. Edwards, and D.T. Brown (1983). Polycaryocyte formation mediated by Sindbis virus glycoproteins. J. Virol. 45:1083-1089.
39. Brown, D.T. (1984). “Alphavirus growth in cultured vertebrate and invertebrate cells.” In M.A. Mayo and K.A. Harrap’s (eds.) Vectors in Virus Biology, pp. 113-133. Academic Press, N.Y.
40. Coombs, K., B. Brown, and D.T. Brown (1984). Evidence for a change in capsid morphology during Sindbis virus envelopment. Virus Res. 1:297-302.
41. Cassell, S., J. Edwards, and D.T. Brown (1984). Effects of lysosomotropic weak bases on infection of BHK-21 cells by Sindbis virus. J. Virol. 52:857-864.
42. Edwards, J., and D.T. Brown (1984). Sindbis virus induced fusion of tissue cultured Aedes albopictus (mosquito) cells. Virus Res. 1:705-711.
43. Adams, R.H., and D.T. Brown (1985). BHK cells expressing Sindbis virus-induced homologous interference allow the translation of nonstructural genes of superinfecting virus. J.Virol. 54:351-357.
44. Brown, D.T., and L. Condreay (1985). Replication of alphavirus in mosquito cells. In “The Viruses,” S. Schlesinger (ed.), pp. 171-207, Academic Press, NY.
45. Edwards, J., and D.T. Brown (1986). Sindbis virus-mediated cell fusion from without is a two-step event. J. Gen. Virol., 67:377- 380.
46. Coombs, K., and D.T. Brown (1986). The penetration of animal cells by viruses. In “Mechanisms of Viral Toxicity in Animal Cells,” L. Carrasco (ed.), pp. 6-19.
47. Condreay, L., and D.T. Brown (1986). Exclusion of superinfecting homologous virus by Sindbis virus infected Aedes albopictus (mosquito) cells. J. Virol. 58:81-86.
48. Ready, M.P., D.T. Brown, J.D. Robertus (1986). Extracellular localization of pokeweed antiviral protein. P.N.A.S. USA 83:5053-5056.
49. Coombs, K., and D.T. Brown (1987). Topological organization of Sindbis virus capsid protein in isolated nucleocapsids. Virus Research 7:131-149.
50. Coombs, K., and D.T. Brown (1987). Organization of the Sindbis virus nucleocapsid as revealed by bifunctional cross- linking agents. J. Mol. Biol., 195:359-371.
51. Condreay, L., and D.T. Brown (1988). Effects of actinomycin D and cyclohexamide on the replication of Sindbis virus in A. albopictus (mosquito) cells. J. Virol., 62:2629-2635.
52. Condreay, L., and D.T. Brown (1988). Suppression of RNA synthesis by a specific antiviral agent produced in Sindbis virus- infected A. albopictus (mosquito) cells. J. Virol., 62:346-348.
53. Knipfer, M., and D.T. Brown (1989). Intracellular transport and processing of Sindbis virus glycoproteins. Virol., 170:117- 122.
54. Coombs, K. and D.T. Brown (1989). Form-determining functions in Sindbis virus nucleocapsids: nucleosomelike organization of the nucleocapsid. J. Virol 63:883-891.
55. Presley, J.F. and D.T. Brown (1989). The proteolytic cleavage of PE2 to envelope glycoprotein E2 is not strictly required for the maturation of Sindbis virus. J. Virol 63:1975- 1980.
56. Anthony, R.A., and D.T. Brown (1991). Protein-protein interactions in an Alphavirus membrane. J. Virol 65:1187-1194.
57. Presley, J.F., R.K. Draper, and D.T. Brown (1991). Defective transport of Sindbis virus glycoproteins in end4 mutant Chinese hamster ovary cells. J. Virol 65:1332-1339.
58. Edwards, J., and D.T. Brown (1991). Sindbis virus infection of Chinese hamster ovary cell mutant defective in the acidification of endosomes. Virol 182:28-33.
59. Presley, J.F., J.M. Polo, R.E. Johnston, and D.T. Brown (1991). Proteolytic processing of the Sindbis virus membrane protein precursor PE2 is nonessential for growth in invertebrate cells but is required for efficient growth in invertebrate cells. J. Virol 65:1905-1909.
60. Miller, M.L., and D.T. Brown (1991). “Alphavirus Infection of Cultured Tissue Cells.” In Kerry F. Harris’ (ed.) Advances in Disease Vector Research, Vol. 8, pp. 107-142.
61. Miller, M.L., and D.T. Brown (1992). Morphogenesis of Sindbis virus in three subclones of Aedes albopictus (mosquito) cells. J. Virol. 66:4180-4190.
62. Paredes, A.M., M.L. Simon, and D.T. Brown (1992). The mass of the Sindbis nucleocapsid suggests it has a T=4 icosahedral symmetry. Virol. 187:329-332.
63. Brown, D.T. (1992). Replication of alphavirus in cultured vertebrate and insect cells. In “Molecular Biology of the Cell,” ed., W. Doerfler. VCH Verlag Sgeselischaft, Weinheim, Germany, pp. 288-303.
64. Anthony, R.P., A.M. Paredes, and D.T. Brown (1992). Disulfide bonds are essential for the stability of the Sindbis virus envelope. Virol. 190:330-336.
65. Brown, D.T., and J. Edwards (1992). Structural changes in alphaviurses accompanying the process of membrane penetration. Seminars in Virol. 3:519-527.
66. Miller, M.L., and D.T. Brown (1993). The distribution of Sindbis virus proteins in mosquito cells as determined by immunofluorescence and immunoelectron microscopy. J. Gen. Virol. 74:293-298.
67. Liu, N., and D.T. Brown (1993). Transient translocation of the cytoplasmic (endo) domain of a type-I membrane glycoprotein into cellular membranes. J. Cell Biol. 120:877-883.
68. Luo, T., and D.T. Brown (1993). Purification and characterization of a Sindbis virus-induced peptide which stimulates its own production and blocks virus RNA synthesis. Virol. 194:44-49.
69. Parades, A.M., D.T. Brown, W. Chiu, R. Rothnagel, R. Johnston, R. Schoep, and B.V.V. Prasad (1993). Three-dimensional structure of a membrane-containing virus. Proc. Nat. Acad. Sci. USA., 90:9095-9099.
70. Abell, B.A., and D.T. Brown (1993). Sindbis virus membrane fusion is mediated by reduction of glycoprotein disulfide bridges at the cell surface. J. Virol., 67:5496-5501.
71. Liu, N., and D.T. Brown (1993). Phosphorylation dephosphorylation events play critical roles in Sindbis virus maturation. J. Virol., 196:703-711.
72. Mulvey, M., and D.T. Brown (1994). Formation and rearrangement of disulfide bonds during maturation of the Sindbis virus E1 glycoprotein. J. Virol. 68:805-812.
73. Luo, T., and D.T. Brown (1994). A 55kDa protein induced in Aedes albopictus (mosquito) cells by antiviral protein. Virol. 200:2060-206.
74. Lee, H., and D.T. Brown (1994). Mutations in an exposed domain of Sindbis virus capsid protein result in the production of noninfectious virions and morphological variants. Virol. 202:390-400.
75. Lee, H., P.D. Ricker and D.T. Brown (1994). The configuration of Sindbis virus envelope proteins is stabilized by nucleocapsid protein. Virology 204:471-474 83.
76. Mulvey, M. and D.T. Brown (1994) Involvement of the Chaperon Protein BIP in the Folding and Assembly of Sindbis Virus Envelope Glycoproteins. J. Virol. 69:1621-1627
77. Bowers, D.F.,B. A. Abell and D.T. Brown (1995). Replication and tissue tropism of the alphavirus Sindbis in the mosquito Aedes albopictus. Virology 212:1-12
78. Rumenapf,t., D.T. Brown, E.G. Strauss, M. Konig, R. Rameriz-Mitchel and J.H. Strauss. (1995) Aura Alphavirus Subgenomic RNA is Packaged into Virions of Two Sizes . J. Virol. 69:1741-1746
79.Carlton, M. and D.T. Brown (1996) Events in the Endoplasmic Reticulum Abrogate the Temperature Sensitivity of Sindbis Virus Mutant TS23. J. Virol. 70:952-959
80. Mulvey,M. and D.T. Brown.(1996) Assembly of the Sindbis Virus Spike Protein Complex. Virology. 219: 125-132
81. Liu N., H. Lee, R. Hernandez, and D.T. Brown. (1996) Mutations in the Endo Domain of Sindbis Glycoprotein E2 Block Phosphorylation, Reorientation of the Endo Domain and Nucleocapsid Binding. Virology 222: 226-246
82. Carlton, M. and D.T. Brown. (1996) Disulfide Bridge Mediated Folding of Sindbis Virus Glycoproteins. J. Virol. 70: 5541-5547
83.Lee, S., K. E. Owen, H-K. Choi, H. Lee, G. Lu, G. Wengler. D. T. Brown, M. Rossmann and R. J. Kuhn. (1996) Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly. Structure. 4: 531-541
84. Carleton M., H. Lee, M. Mulvey and D.T. Brown (1996) The Role of PE2 in Formation and Maturation of the Sindbis Virus Spike. J. Virol.71: 1558-1566
85.Karpf, A.R., J.M. Blake and D. T. Brown (1997)Characterization of the infection of Aedes albopictus cell clones by Sindbis virus. Virus Research. 50 : 1-13.
86. Karpf, A. R., E. Lenches, E.G. Strauss, J.H. Strauss and D.T. Brown (1997) Superinfection Exclusion of Alphaviruses in Three Mosquito Cell lines Persistently Infected with Sindbis Virus. J. Virol. 71:7119-7123
87. Carleton M.C. and D.T. Brown (1997) The Formation of Intra molecular Disulfide Bridges is Required for the Induction of Sindbis Virus Mutant ts23 Phenotype. J. Virol. 71: 7696-7703
88. Karpf, A.R. and D.T. Brown (1998)Comparison of Sindbis virus-Induced pathology in mosquito and vertebrate cell cultures. Virology. 240: 193-201
89. Hernandez, R., H. Lee, C. Nelson and D. T. Brown (2000) A Single Deletion in the Membrane Proximal Region of the Sindbis Virus Glycoprotein E2 Endodomain Blocks Virus Assembly. J. Virol. 74: 4220-4228
90. Phinney, B. P., K. Blackburn and D.T. Brown (2000) The Surface Conformation of the Sindbis Virus Glycoproteins E1 and E2 at Neutral and Low pH as Determined by Mass-Spectroscopy Based Mapping. J. Virol. 74: 5667-5678
91. Brett S. Phinney and Dennis T. Brown (2000) Sindbis Virus Glycoprotein E1 is Divided into Two Discrete Domains at Amino Acid 129 by Disufide Bridge Connections. J. Virol. 74: 9313-9316
92. Hernandez, R., T. Luo1 and D.T. Brown (2000) Exposure to low pH is not required for the penetration of mosquito cells by Sindbis virus. J.Virol. 75: 2010-2013
93.Pletnev, S., W. Zhang, S. Mukhopadhyay, B. Fisher, R. Hernandez, D. T. Brown, T. S. Baker, M. G. Rossmann and R. J. Kuhn (2001). Location of Carbohydrate Sites on Sindbis Virus Glycoprpteins Shows that E1 Forms an Icosahedreal Scaffold. Cell: Vol 105. 127-136
94.Bowers, D. F., Coleman, C. G., and Brown, D. T. (2003). Sindbis virus-associated pathology in Aedes albopictus (Diptera: Culicidae). J Med Entomol 40(5), 698-705.
95.Ferreira, D. F., Hernandez, R., Horton, M., and Brown, D. T. (2003). Morphological variants of Sindbis virus produced by a mutation in the capsid protein. Virology 307(1), 54-66.
96.Hernandez, R., Nelson, S., Salm, J. R., Brown, D. T., and Alpert, A. J. (2004). Rapid preparative purification of West Nile and Sindbis virus PCR products utilizing a microbore anion-exchange column. J Virol Methods 120(2), 141-9.
97.Hernandez, R., Sinodis, C., Horton, M., Ferreira, D., Yang, C., and Brown, D. T. (2003). Deletions in the transmembrane domain of a sindbis virus glycoprotein alter virus infectivity, stability, and host range. J Virol 77(23), 12710-9.
98.Paredes, A. M., Ferreira, D., Horton, M., Saad, A., Tsuruta, H., Johnston, R., Klimstra, W., Ryman, K., Hernandez, R., Chiu, W., and Brown, D. T. (2004). Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion. Virology 324(2), 373-86.
99. Hernandez, R., Ferreira, D., Sinodis, C., Litton, K. & Brown, D. T. (2005). Single amino acid insertions at the junction of the sindbis virus E2 transmembrane domain and endodomain disrupt virus envelopment and alter infectivity. J Virol79, 7682-97.
100. Nelson, S., Hernandez, R., Ferreira, D. & Brown, D. T. (2005). In vivo processing and isolation of furin protease-sensitive alphavirus glycoproteins: a new technique for producing mutations in virus assembly. Virology 332, 629-39.
101: Sharp, J. S., S. Nelson, D. Brown, and K. B. Tomer. 2006. Structural characterization of the E2 glycoprotein from Sindbis by lysine biotinylation and LC-MS/MS. Virology. 348:216-223
102: West, J., and D. T. Brown. 2006. The role of a conserved tripeptide in the endodomain of Sindbis virus glycoprotein E2 in virus assembly and function. J. Gen Virol 87:657-654.
103: Caryn L. Heldt,a Raquel Hernandez,b Usharani Mudiganti,b Patrick V. Gurgel,c Dennis T. Brown,b Ruben G. Carbonell,a* 2006 A colorimetric assay for viral agents which produce cytopathic effects , J Virol Meth. In Press
104: John West, Raquel Hernandez, Davis Ferreira and Dennis T. Brown* 2006 Mutations in the endodomain of Sindbis virus Glycoprotein E2 define sequences critical for virus assembly. J. Virol. 80:4458-4468
105: Raquel Hernandez*, Christine Sinodis and Dennis T. Brown (2006) Sindbis Virus: Propagation, Quantitation, and Storage. Current Protocols in Microbiology
106: Whitehurst, C. B., Willis, J. H., Sinodis, C. N., Hernandez, R., and Brown, D. T. (2006). Single and multiple deletions in the transmembrane domain of the Sindbis virus E2 glycoprotein identify a region critical for normal virus growth. Virology 347(1), 199-207.
107: Mudiganti, U., R. Hernandez, D. Ferreira, and D. T. Brown. 2006. Sindbis virus infection of two model insect cell systems–a comparative study. Virus Res 122:28-34.
108: Wang, G., R. Hernandez, K. Weninger, and D. T. Brown. 2007. Infection of cells by Sindbis virus at low temperature. Virology 362:461-7.
109. Whitehurst, C. B., E. J. Soderblom, M. L. West, R. Hernandez, M. B. Goshe, and D. T. Brown. 2007. Location and role of free cysteinyl residues in the sindbis virus e1 and e2 glycoproteins. J Virol 81:6231-40.
111Hernandez, R., Paredes, A., and Brown, D. T. (2008). Sindbis virus conformational changes induced by a neutralizing anti-E1 monoclonal antibody. J Virol 82(12), 5750-60.
112Kononchik, J. P., Jr., Nelson, S., Hernandez, R., and Brown, D. T. (2009). Helical virus particles formed from morphological subunits of a membrane containing icosahedral virus. Virology 385(2), 285-93.
113. Nanda, K., R. Vancini, et al. (2009). “A high capacity Alphavirus heterologous gene delivery system.” Virology 390(2): 368-373.
114. Hafer, A., Whittlesey, et.al. (2009). “ Differential incorporation of cholesterol by Sindbis virus grown in mammalian or insect cells” J Virol 83 (18): 9113-21.
115. Brown, D.T. and Raquel Hernandez. (2010). Host Range Virus Mutants as Vaccines for Arthropod Vectored Viruses. Nova Acta Leopoldina NF 98, Nr. 361, 201-213.
116 Mudiganti, U., Hernandez, R., and Brown, D. T. (2010). Insect response to alphavirus infection–establishment of alphavirus persistence in insect cells involves inhibition of viral polyprotein cleavage. Virus Res 150(1-2), 73-84.
117 Brown, D.T. and Raquel Hernandez. (2010). Host Range Virus Mutants as Vaccines for Arthropod Vectored Viruses. Nova Acta Leopoldina NF 98, Nr. 361, 201-213.
118 He, L., Piper, A., Meilleur, F., Myles, D. A., Hernandez, R., Brown, D. T., and Heller, W. T. (2010). The structure of Sindbis virus produced from vertebrate and invertebrate hosts as determined by small-angle neutron scattering. J Virol 84(10), 5270-6.
119 Hernandez R, Brown DT.Growth and maintenance of baby hamster kidney (BHK) cells. Curr Protoc Microbiol. 2010 May;Chapter 4:Appendix 4H.
120 Hernandez, R., Brown, D.T., 2010a. Growth and maintenance of chick embryo fibroblasts (CEF). Current protocols in microbiology Appendix 4, 4I.
121 Hernandez, R., Brown, D.T., 2010b. Growth and maintenance of mosquito cell lines. Current protocols in microbiology Appendix 4, 4J.
122 Hernandez R, Sinodis C, Brown DT.Sindbis virus: propagation, quantification, and storage. Curr Protoc Microbiol. 2010 Feb;Chapter 15:Unit15B.1.
123 Hunt, S. R., Hernandez, R., and Brown, D. T. (2011). Role of the Vacuolar-ATPase in Sindbis Virus Infection. J Virol 85(3), 1257-66.
124 Kononchik, J. P., R. Vancini, et al. (2011). “Alphavirus adsorption to mosquito cells as viewed by freeze fracture immunolabeling.” Virology 415(2): 132-140
125. Joseph P Kononchik, Raquel Hernandez and Dennis T Brown “An Alternative Pathway for Alphavirus Entry”Virology Journal 2011, 8:304
126 Smith, K.M., Nanda, K., Spears, C.J., Ribeiro, M., Vancini, R., Piper, A., Thomas, G.S., Thomas, M.E., Brown, D.T., Hernandez, R., 2011. Structural mutants of dengue virus 2 transmembrane domains exhibit host-range phenotype. Virol J 8, 289.
127. Lilin He, Amanda Piper, Flora Meilleur, Raquel Hernandez, William T. Heller, Dennis T. Brown. 2011 Conformational changes in Sindbis virus induced by decreased pH revealed by small-angle neutron scattering J Virol 84(10): 5270-5276.
128. Ricardo Vancini; Angel Paredes; Mariana Ribeiro; Kevin Blackburn; Davis Ferreira; Joseph P. Kononchik Jr. Raquel Hernandez and Dennis Brown, 2012. Espirito Santo Virus: A new Birnavirus that replicates in insect cells Journal of virology 86(5): 2390-2399 Featured on journal cover
129. Brown, D. T. and R. Hernandez (2012). “Infection of cells by alphaviruses.” Advances in experimental medicine and biology 726: 181-199.
130. Vancini R, Kramer LD, Ribeiro M, Hernandez R, and Brown D(2013) Flavivirus infection from mosquitoes in vitro reveals cell entry at the plasma membrane.
Virology 435: 406-14
131. Vancini, R., G. Wang, D. Ferreira, R. Hernandez and D.T. Brown (2013). “Alphavirus genome delivery occurs directly at the plasma membrane in a time- and temperature-dependent process.” J Virol 87(8): 4352-4359. Featured on Journal Cover
132. Piper A, Ribeiro M, Smith KM, Briggs CM, Huitt E, Nanda K, Spears CJ, Quiles M, Cullen J, Thomas ME, Brown DT and Hernandez R. (2013) Chikungunya virus host range E2 transmembrane deletion mutants induce protective immunity against challenge in C57BL/6J mice. Journal of virology 87: 6748-57
133. Briggs CM, Smith KM, Piper A, Huitt E, Spears CJ, Quiles M, Ribeiro M, Thomas ME, Brown DT,and Hernandez R .(2014) Live Attenuated Tetravalent Dengue Virus Host Range Vaccine Is Immunogenic in African Green Monkeys following a Single Vaccination. Journal of virology 88: 6729-6742
134.Raquel Hernandez , Dennis T. Brown, Angel Paredes (2014) Structural differences observed in Arboviruses of the Alphavirus and Flavivirus Genera. Advances in Virology Volume 2014, Article ID 259382, 24 pages (This is a review)
135.Vancini, R., R. Hernandez, and D. Brown. 2015. Alphavirus entry into host cells. Prog Mol Biol Transl Sci 129:33-62. (This is a review chapter)